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Andexxa is a protein that reverses the effects of certain anticoagulant medications that are used to treat or prevent blood clots Andexxa works by acting as a decoy for oral and injectable fxa inhibitors, which target and bind to fxa, allowing them to exert their anticoagulant effect. Andexanet alfa, sold under the brand name andexxa among others, is an antidote for the medications rivaroxaban and apixaban, when reversal of anticoagulation is needed due to uncontrolled bleeding
Astrazeneca's anticoagulant reversal agent andexxa was given an accelerated approval by the fda in 2018, but the company's plan to get that upgraded to a full approval is facing some pushback. The effect of andexanet alfa, an agent that reverses the effects of factor. Provides prescribing information for andexxa, including medication guide and instructions for use.
Patients with acute intracerebral hemorrhage who are receiving factor xa inhibitors have a risk of hematoma expansion
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