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Ion channels are crucial components of cellular excitability and are involved in many neurological diseases Introduction since its molecular identification roughly 25 years ago by lee and colleagues (1), the sodium leak channel nalcn has emerged as an important regulator of cellular excitability Leak channels, also referred to as leakage or passive channels, represent the most basic type of ion channel found in cells, essential for shaping the membrane's potential difference
This perpetual openness enables ions to move across the membrane according to their respective. [1][2] they belong to the superfamily of cation channels. Sodium channel c (dark green) is the sodium channel
Sodium ions 'a' are (light green)
Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (na +) through a cell's membrane
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