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What is a troponin test Troponin levels are measured with a blood test, and high levels may be a sign of heart damage. A troponin test looks for the protein troponin (there are two forms related to your heart, troponin i and troponin t) in your blood
Normally, troponin stays inside your heart muscle’s cells, but damage to those cells — like the kind of damage from a heart attack — causes troponin to leak into your blood Numerous disorders are capable of causing troponin elevation in critical illness (e.g., sepsis, chronic. Higher levels of troponin in your blood also mean more.
(see diagnosis of acute myocardial infarction, section on 'definitions'.) however, troponin is not specific for acute thrombotic occlusion of a coronary artery, the most common precursor to acute myocardial infarction.
Rapid advances in immunoassay technologies and the international adoption of traceable troponin calibration standards have allowed manufacturers to develop and calibrate troponin assays with unprecedented analytic sensitivity and precision. There are many clinical conditions other than myocardial infarction that cause troponin elevation Thus, the physician should be aware of the wide spectrum of disease states that may result in troponin elevation and have a clear understanding of the related pathophysiology to effectively make a differential diagnosis. Troponin is often positive among critically ill patients using standard troponin assays, ~40% of patients in an icu will have an elevated troponin
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